Introduction to role: Join our dynamic team at AstraZeneca as a Research Associate in Process Development. Based in Santa Monica, CA, you will be supporting and contributing to the design and execution of studies to develop and optimize clinical manufacturing processes of Neogene portfolio of engineered T cell therapies. This role reports to the Senior Scientist, Process Development.
Accountabilities: As a Research Associate, you will manage process development studies to develop, optimize, scale-up and transfer cGMP manufacturing processes. You will carry out flow cytometry and cell-based assay experiments for the characterization and optimization of cell therapy manufacturing processes. You will also perform cell culture of T cells in multiple formats including flasks, bags, and bioreactors. Collaborating within the project team to interpret study results and contribute to technical discussions for subsequent study design is also part of your role. You will prepare and review experimental proposals, technical reports, SOPs, and manufacturing batch records. Working collaboratively within the PD group and cross-functionally with other groups to meet Technical Operation organization goals is essential.
Essential Skills/Experience: A minimum of 6 months practical experience with Flow CytometryHands-on experience in primary cell culture, specifically in T cells is highly desirableKnowledge of cGMP manufacturing and regulations and practical experience in GMP operations is highly desirableKnowledge of statistical analysis for process developmentAbility to think critically, analytically and have demonstrated troubleshooting and problem-solving skills based on deductive reasoningMS degree in Immunology, Cell Biology, Molecular Biology, Bioengineering, or relevant degrees or similar BS degree with 1.5+ years relevant experience within the pharmaceutical or biotech industriesAre you ready to be challenged in your everyday work? Do you have the drive and determination to overcome barriers and make things happen? If so, apply today and join us in making a difference!
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