At Lilly, we unite caring with discovery to make life better for people around the world. We are a global healthcare leader headquartered in Indianapolis, Indiana. Our employees around the world work to discover and bring life-changing medicines to those who need them, improve the understanding and management of disease, and give back to our communities through philanthropy and volunteerism. We give our best effort to our work, and we put people first. We're looking for people who are determined to make life better for people around the world.
The Early Preclinical Development (EPD) Team is seeking an Associate Scientist with experience in inner ear histology to support discovery and IND-enabling animal studies. The ideal candidate will have experience in histologic techniques specific to the inner ear, such as microdissection of the mouse and non-human primate (NHP) inner ear tissues into discrete anatomical regions, and further processing of these tissues using various histologic techniques, in addition to imaging, analysis, and preparation of data for presentation. Cross-functional work may be required to advance Company goals. The successful candidate will be self-motivated and creative, with a desire to succeed at the highest level in a highly collaborative and fast-paced environment.
Job Responsibilities:Perform mouse and NHP inner ear microdissectionsPerform NHP temporal bone extraction and processingPrepare inner ear tissues for embedding and preparation for frozen sectionsPreparation of inner ear tissues for molecular analysesPerform immunohistochemistryPerform epifluorescent imaging, cochlear frequency mapping, and confocal microscopyProduce graphs and charts from histologic dataPreparation of histologic images for presentationDevelopment and/or review of immunohistochemistry protocols and image acquisition strategiesInventory ordering and database managementCollaborate closely with cross-functional teams and external groups to coordinate execution of complex studiesIdentify and communicate potential efficiencies for day-to-day operationsWeekend work may be required at timesBasic Qualifications: Bachelor's Degree with 0+ years of experience, hands-on experience with inner ear biology is preferred.Additional Skills and Preferences: Experience in solving scientific problems and/or image analysis using programming languagesExperience and programming skills in at least one language such as Python or MATLABKnowledge of cochlear anatomy, cochlear microdissection (whole-mount and sections), and methods for histological preparation of inner ear tissues requiredExperience with modern imaging techniques; epifluorescent and confocal microscopy requiredExcellent computer skills; proficiency in Microsoft Office (Word, Excel, Teams, PowerPoint, Outlook, Adobe Suite)Experience with image analysis software (ImageJ, Amira, LasX, Imaris); may include codingExcellent laboratory technical lab skills (pipetting, reagent preparation, liquid handling)
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