Research Associate – Research and Development – In vitro Our Client is a molecular engineering company focused on creating best-in-class in vivo therapies that permanently treat the underlying cause of disease. Founded by CRISPR inventors and leading molecular engineers, out client is overcoming the limitations of current genome editing technologies by developing custom engineered enzymes and delivery modalities as part of a proprietary, evergreen CRISPR by Design™ platform for CRISPR-based genetic medicine.
We are seeking a highly creative, passionate, and motivated individuals to join us in our quest to bring the next generation of CRISPR-based therapeutics into the IND enabling framework. The candidate should have a passion for working collaboratively with biologists and bioengineers to enable building the necessary tools for meeting the new frontier of CRISPR based therapeutics.
Key Responsibilities: The primary responsibilities of this role will be to plan, perform and analyze experiments to support the discovery and development of new therapeutics. These will include:
Perform cell culture work, including thawing, maintaining, expanding, cryopreserving immortalized and primary cell linesPlan and execute cell-based assays (delivery, microscopy)Perform DNA/RNA/protein isolation from mammalian cellsAnalyze DNA/RNA levels using PCR methodsAnalyze protein expression using western blot, JESS and/or ELISAPrepare aliquots of media, reagents, and inventory managementFollow standard operating procedures, maintain accurate records in electronic notebooks, and adhere to safety protocolsPlan and perform experiments and analyze data with supervisionRequired Skills and Background: A BS/BA in Biology, or closely related field with at least 4+ years of lab experience in biopharma industryProven hands-on experience with sterile technique for handling and growing mammalian cell linesDemonstrated experience with techniques for DNA/RNA/Protein isolation and analysisAbility to work both independently and collaboratively in a fast-paced, interdisciplinary research team.Preferred Skills and Background: Familiarity with CRISPR technologies and therapeutic approachesExperience running high throughput assays
